Mehmet Bostancıklıoğlu, PhD
Department of Physiology
As a dedicated researcher with a Ph.D. in Physiology, my primary focus lies in exploring the complex relationship between glial biology, gut microbiota, and memory. Currently, I am pursuing postdoctoral research at Université Catholique de Louvain while simultaneously working towards a second bachelor's degree.
Research Interests
My research interest lies at the intersection of neuroscience and microbiology, with a primary focus on understanding the complex relationship between the gut microbiota and the development and progression of Alzheimer's disease and other neurological disorders. My work spans from exploring the role of gut microbiota in the pathogenesis of Alzheimer's disease to investigating the interactions between Alzheimer's disease, autophagy, and inflammation. Furthermore, I delve into the effects of intestinal bacterial flora on Alzheimer's disease, memory formation and retrieval processes, as well as endocannabinoid signaling in the aging brain.
In addition to my primary focus on Alzheimer's disease, my research also covers broader aspects of neurophysiology, including neuromodulation of memory formation and extinction, the role of myelin in the microbiota-gut-brain axis, and the impact of local myelin damage in the hippocampus on gut microbiome profiles and memory. Through my research, I aim to provide valuable insights into the intricate connections between gut microbiota, brain function, and neurological disorders, with the ultimate goal of contributing to the development of novel therapeutic strategies for the prevention and treatment of these conditions.
Publications
Local myelin damage in the hippocampus fluctuates gut microbiome profile and memory, Journal of Psychiatric Research, (2023)
Non-invasive MR imaging of human brain lymphatic networks with connections to cervical lymph nodes, Nature Communication, (2022)
Unexpected awakenings in severe dementia from case reports to laboratory, Alzheimer's & Dementia: The Journal of Alzheimer's Association